28 results
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs and Symptoms ... Acute onset of skin ... >2 of: • skin ... /mucosal symptoms ... #Anaphylaxis #pathophysiology
Monkeypox

What?
Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus
Viral zoonotic disease that is
28 days - Skin ... of the systemic symptoms ... bleeding, or other symptoms ... visual acuity Skin ... damage • Skin
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... diabetes Key signs/symptoms ... hypovolemia (dry MM, skin
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
old; F>M Signs/Symptoms ... - Vasculitic skin ... Temporal #Arteritis #Pathophysiology ... Diagnosis #Signs #Symptoms
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
tightening of skin ... CREST #Syndrome #Pathophysiology ... Diagnosis #Signs #Symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
(SLE) Signs / Symptoms ... Xeroderma (Dry skin ... Sjogrens #Syndrome #Pathophysiology ... Diagnosis #Signs #Symptoms
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... tunnel, OSA, Incr skin ... endocrinology #pathophysiology
Reactive Arthritis
 • Inflammation of joints (commonly large joints)
    - Asymmetric Oligoarthritis: Joint
Transient • Skin ... ReactiveArthritis #pathophysiology ... diagnosis #signs #symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
manifestations Skin ... Inflammation of skin ... granulomas under skin ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Psoriatic Arthritis: Pathogenesis and Clinical findings

In tendons and connective tissues:
 • Enthesitis  - Pain/tenderness over
are inflamed In skin ... Psoriatic plaques on skin ... PsoriaticArthritis #pathophysiology ... diagnosis #signs #symptoms