21 results
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 • Focal: Simple, Complex
 • Generalized: Absence,
Causes of Seizures ... Recreational drugs, Poisons ... Neurocysticercosis, PML ... Diagnosis #Algorithm #Causes
Tree in Bud Sign
The Tree-in-Bud sign represents Endobronchial spread in a linear branching pattern and centrilobular
It is caused by ... actually seen in all causes ... pneumonia, congenital causes ... Devpriyo Pal @drdevrad ... radiology #ChestCT #pathophysiology
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
URT inflammation causes ... severe swelling causes ... & hemorrhagic rash ... Vesicular & pruritic rash ... peds #pediatrics #pathophysiology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
blood - Tubular Poisons ... keto-acids) -> Poisons ... Release of purine bases ... Hyperuricemia #Pathophysiology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... Causes: 1) Exfoliative ... #Dermatology #Rash
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
convoluted tubule (PCT ... organic acids and bases ... filtered Na+/K+/Cl ... filtered Na+ and Cl ... Segments #Function #Pathophysiology
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... shaking chills • Rash ... is rare (< 10% cases ... ), cough (30% cases
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
reaction -> Benign Rash ... Systemic effect -> Nausea ... hyponatremia, rash ... #SideEffects #Pathophysiology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... plugging -> Discoid Rash ... Malar (butterfly) Rash ... Manifestations #pathophysiology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
For pituitary masses ... FSH, TSH, ACTH, PRL ... Headaches • Nausea ... mnemonic #GLFTAP #pathophysiology