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diagnosis differential algorithm causes classification hematology disease signs symptoms syndrome types behcets complications criteria cryofibrinogenemia cryoglobulinemic cryoglobulins cutaneous glomerulonephritis management
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
Vasculitis 1 ... 3 types 2) Vasculitis ... phenomenon • Ulcers ... #Vasculitis #Diagnosis ... #Rheumatology #
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
nodules, Deep ulcers ... Urticarial/LCV) - Cryoglobulinemic ... : • Behcet Disease ... #skin #dermatology ... #rheumatology #
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
idiopathic oral ulcers ... Recurrent genital ulcers ... Uveitis or retinal vasculitis ... oral and genital ulcers ... Diagnosis #criteria #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia ... Purpura - Skin ulcers ... (e.g. systemic lupus ... classification #rheumatology ... #vasculitis
Mucous Membrane Disorder - Differential Diagnosis Algorithm Erosions/Ulcers/Blisters - Primary Dermatologic Diseases •
Algorithm Erosions/Ulcers ... Blisters - Primary Dermatologic ... recurrent, punched out ulcers ... • Systemic lupus ... disease) • Behcet's
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
livedo reticularis, ulcers ... : • Behçet Syndrome ... genital aphthous ulcers ... such as systemic lupus ... differential #diagnosis #rheumatology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Skin Ulcers by Etiology ... insufficiency • Vasculitis ... Thalessemia • Cryoglobulinemia ... Cryptococcosis #Ulcers ... ulcerative #skinrash #dermatology
Causes of Pharyngitis - Differential Diagnosis Infectious: • Bacterial: Group A Strep, Group B and C Strep,
Viruses Autoimmune: Lupus ... , Behcet syndrome ... , ANCA vasculitis ... Drug-induced mucosal ulcers
Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Cryoglobulinemia ... phenomenon, Digital ulcers ... MatthewHoMD #Cryoglobulinemia ... Classification #Types #hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Post-strep GN, Lupus ... Nephritis, Cryoglobulinemia ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
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