28 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... of SLE versus DIL ... life-threatening • Treatment ... #Diagnosis #Management ... #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis ... #management #treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
months to years) Systemic ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
only curative treatment ... Myelodysplastic #Syndrome #MDS ... #Diagnosis #Management ... #treatment #hematology ... #oncology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
solid cancers • Systemic ... Complications: MAS ... , Visceral, DIC, ... #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
episode (30%) Systemic ... synovitis (40%) Treatment ... Disease #AOSD #rheumatology ... #diagnosis #management ... #treatment
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... eruption that may ... Criteria for Diagnosis ... disease: symptomatic treatment ... #diagnosis #management
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
, breast CA - Hematologic ... ’s syndrome - Lupus ... Treatment: - Systemic ... Sweet #Syndrome #diagnosis ... #dermatology #oncology