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hematology nephrology syndrome causes classification rheumatology infectiousdiseases leukemia workup acute algorithm cancer chronic dermatology gastroenterology hiv infections kidney mds myelodysplastic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... Leukemia #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... chemotherapy for low-risk disease ... #Leukemia #oncology ... hematology #hemeonc #diagnosis ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... cells can indicate disease ... • Neutropenia, anemia ... microglobulin Treatment ... #workup #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... Allogeneic stem cell ... only curative treatment ... #Management #treatment ... #hematology #oncology
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma Diagnosis ... and Management ... demineralization) • Renal disease ... plasma clonal cell ... #Management #oncology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
on the left Myeloblast ... Neutrophil (Normal) Differential ... Diagnosis: • ... • Autoimmune diseases ... #differential #
Dyspnea - Considerations with Malignancy Directly Malignancy Related: - Lymphangitic spread to lung - Malignant pleural effusion
metastases Treatment ... Radiation induced disease ... - Cytopenias (anemia ... dyspnea #algorithm #differential ... #diagnosis #oncology
Hansen's Disease (Leprosy) • Transmission - not completely understood, ?nasal droplets • Symptoms appear ~5 years
Lepromatous leprosy (LL ... plasma cells, lymphocytes ... and numerous AFB Treatment ... #Leprosy #diagnosis ... #management #treatment
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Disease Acute ... Supportive with treatment ... hepatomegaly and anemia ... hepatology #hepatitis #differential ... #diagnosis
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
malignancies Treatment ... #AKI #Cancer #Oncology ... #Differential # ... Diagnosis #Classification ... #Nephrology
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