41 results
differential management chronic hemolytic rheumatology classification dermatology disease hemolysis lymphocytic macrocytic mds myelodysplastic pancytopenia pathophysiology syndrome testing thrombocytopenia thrombocytosis wbc
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Symptoms: • Fatigue ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Algorithm and Causes ... breakdown • Anaemia ... Hemolysis #Hemolytic #Anemia ... #Causes #Workup ... #Hematology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... sweats • Extreme fatigue ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
of hematologic ... bruising/bleeding, fatigue ... hepatomegaly • Labs: anemia ... #Algorithm #hematology ... #WBC #Leukemoid
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Algorithm Reactive ... Bleeding, Infection, Fatigue ... #Algorithm #Causes ... #Hematology #Oncology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... - Differential Diagnosis ... Myelofibrosis Stem cell ... Toxins • Aplastic Anemia ... #Algorithm #Causes
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... ITP • SLE • CLL ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Algorithm Spurious ... Chronic Myelogenous Leukemia ... Iron deficiency anemia ... #Algorithm #Causes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute leukemia ... Management #treatment #hematology ... #oncology
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
- Differential Diagnosis ... Algorithm Primary ... Anemia - Others ... #Differential #Diagnosis ... #causes
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