28 results
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Features of hematologic ... hepatomegaly • Labs: anemia ... after initial Rx), basophilia ... #Leukocytosis #Differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Artifact (redo CBC ... effect following treatment ... Iron deficiency anemia ... Thrombocytosis #Differential
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... , CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... Blood #Disorders #hematology ... #Markers #Differential
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... Eosinophils 3) Basophils ... #Diagnosis #Dermatology ... Nikolsky #Algorithm #Differential
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
on the left Myeloblast ... Neutrophil (Normal) Differential ... #differential # ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... Volume (MCV) - Differential ... MCV/RBC<13, +/- basophilic ... #elevatedMCV #Differential ... Algorithm #Causes #Hematology
Causes of Aplastic Anemia

#Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Causes of Aplastic Anemia ... #Aplastic #Anemia ... #Causes #Pathophysiology ... #Pathology #Treatment ... #Management #Differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Thrombocytosis #Platelets #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... thalassemia, S Lepore • Basophilic ... #Differential # ... Algorithm #workup #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... • Blood smear: Differential ... diagnosis #management #treatment ... #rheumatology