19 results
diagnosis algorithm anemia hemolytic oncology causes extravascular hepatitis intravascular liver transaminitis workup abnormal agglutinin aih anemias antibody atlas bandemia bloodcell
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
: • Autoimmune ... (AIHAs) • Alloimmune ... • Extrinsic RBC ... • Intrinsic RBC ... Diagnosis #Algorithm #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... • Alloimmune ... elliptocytosis - RBC ... Extravascular #Differential ... Algorithm #Causes #Hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... 1) DIAGNOSE AIHA ... ↑ LDH • Anti-RBC ... • Blood smear: Differential ... #diagnosis #management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(AIHA) "Warm" ( ... (AIHA)"Cold" (usually ... • Intrinsic RBC ... Extravascular #Causes #differential ... #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... 2) External (RBC ... Membrane): - Autoimmune ... 3) Internal (RBC ... Diagnosis #hematology
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Pancytopenia - Differential ... Initial Workup: CBC ... reticulocyte count, LFTs ... ↑ Destruction (hemolysis ... Diagnosis #Algorithm #hematology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Viral, Ischemia, AIH ... Ducts - PBC ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... hypertension • Unusual RBC ... acanthocytes - Consider RBC ... elliptocytosis, autoimmune ... Algorithm #workup #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... spherocytosis, Autoimmune ... Agglutinate: Cold autoimmune ... #Morphology #differential ... #diagnosis #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Approach to Anemia - Differential ... -100): • Non-hemolytic ... Spherocytosis, G6PD, PK, HbC ... - Extrinsic: Autoimmune ... #Diagnosis #hematology
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