18 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Leukemia, Tumour ... Non-lmmune: • HELLP ... #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... child * Severe cases ... #AFLP #obstetrics ... #hematology #diagnosis ... #table #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... child * Severe cases ... #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... Chronic Myelogenous Leukemia ... following EtOH induced thrombocytopenia ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... - Pregnancy: HELLP ... #Differential #Diagnosis ... #Framework #hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Septic shock, Obstetric ... promyelocytic leukemia ... Summary #table #comparison ... #diagnosis #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
features: Hemolysis, Thrombocytopenia ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Neutrophils • Immature/Myeloblasts ... infiltrates (anemia, thrombocytopenia ... #Hematology #Oncology ... #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... old, ~10,000 new cases ... transformation to acute leukemia ... Management • ... #hematology #oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... coagulation (DIC) - HELLP ... microangiopathy: Thrombotic thrombocytopenic ... #hematology #anemia