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hematology differential algorithm management anemia workup causes clinical pocus oncology testing pathophysiology treatment antibody arthritis hepatology intravascular joint laboratory obgyn
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential Diagnosis ... • Extrinsic RBC ... • Intrinsic RBC ... #Differential #Diagnosis ... #Algorithm #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Algorithm Decreased WBCs ... Normal/lncreased WBCs ... Polychromatic Macrocytes, RBC ... Spherocytes, RBC
Pathophysiology of Hemolytic Anemia - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects) -
Pathophysiology of Hemolytic ... - Defects in RBC ... - Defects in RBC ... Pathophysiology #Hemolytic ... #Anemia #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Antibody Autoimmune Hemolytic ... Anemia 1) DIAGNOSE ... ↑ LDH • Anti-RBC ... #Anemia #diagnosis ... management #treatment #rheumatology
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Common RBC Inclusions ... Asplenism, Severe hemolytic ... Sickle cell, MDS #RBC ... Inclusions #Bodies #diagnosis ... #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... Morphology Microcytic RBC ... Bite Cell RBC: G6PD ... #differential #diagnosis ... #hematology #microscopy
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... for Hemolysis - ... • Intrinsic RBC ... #differential #diagnosis ... #hematology #anemia
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... 2) External (RBC ... 3) Internal (RBC ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis ... - Differential Diagnosis ... elliptocytosis - RBC ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Decreased RBC ... Infiltration Increased RBC ... Thalassemia • RBC ... Disorder • RBC
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