12 results
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - ... Differential Diagnosis ... Myelofibrosis • Chronic Myeloid ... Leukemia - BWH ... #Platelets #hematology
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
Diagnosis Algorithm ... • Neoplastic (Leukemia ... #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... #Platelets #Differential ... #Diagnosis #Algorithm ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Diagnosis Algorithm ... Chronic Myelogenous Leukemia ... effect following treatment ... Diagnosis #Algorithm ... #Causes #Hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Diagnosis Algorithm ... anemia, ↑ MCV, ↑/↓ platelets ... #Diagnosis #Algorithm ... #hematology #WBC ... #Leukemoid
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse Lymphadenopathy ... Diagnosis Algorithm ... #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... ALL) - PAS, TdT Lymphadenopathy ... Blood #Disorders #hematology ... #Diagnosis #Algorithm
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... (myeloid)↑ • Mature ... basophilia, and thrombocytosis ... #Hematology #Oncology ... #Diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... (NHL) ~60% - lymphadenopathy ... Treated Like Acute Leukemias ... pathophysiology #Hematology ... algorithm
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
, or all three myeloid ... • Hairy Cell Leukemia ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology