48 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
80%) - Proximal Weakness ... 10%) - Proximal Weakness ... femoral heads • Myopathy ... (Also caused by ... Complications #pathophysiology
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Causes of Proximal ... Muscle Weakness ... Mimic Inflammatory Myopathy ... Mitochondrial myopathy ... #differential #causes
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Causes of Peripheral ... Weakness - With ... • No Objective Weakness ... Oculomotor • Myopathy ... Diagnosis #Algorithm #Causes
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... Elevation (Pain > Weakness ... Subacute to Chronic Causes ... (Weakness > Pain ... PROXIMAL MUSCLE WEAKNESS
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Weakness without ... No Objective Weakness ... • Congenital Myopathy ... Diagnosis #Algorithm #Causes
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Mitochondrial myopathy ... Neuromuscular #Weakness ... #Causes #differential
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Generalized Weakness ... I am weak": • Myopathy ... #Generalized #Weakness ... Differential #Diagnosis #causes
Bell's Palsy
Bell’s Palsy is a damage, acute weakness, or paralysis of the Facial nerve (7th CN),
damage, acute weakness ... an identifiable cause ... The cause is unknown ... neurology #anatomy #pathophysiology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
/paralysis - Weakness ... Non-compressive Spinal Cord Causes ... - Radiation myelopathy ... - Radiation myelopathy ... Back pain • Weakness
Benzodiazepines: Mechanism of Action and Side Effects
 • Decr spinal cord activity -> Muscle relaxant
slurred speech, weakness ... Benzodiazepines #Psychiatry #Pharmacology ... #pathophysiology