27 results
Invasive Candidiasis (IC)

Diagnosis:
Culture:
 • Gold standard, but Slow (~2-3 days), 50% sensitivity
 • Blood Sample
 •
Tests Conduct antifungal ... Line Targeted Treatment ... Funduscopic Exam • CVC ... • Infectious Diseases ... candida #auris #treatment
Krabbe Disease 

Check out this interesting case of Krabbe disease, a rare genetic leukodystrophy. Diagnosis was
Krabbe Disease ... case of Krabbe disease ... testing and expedite treatment ... failure, cerebellar ataxia ... MarkMamloukMD #Krabbe #Disease
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... Motor dysfunction: myoclonic ... incontinence, apraxia
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Inflammatory bowel disease ... dental fixatives, Treatment ... of Wilson's disease ... Metabolic: Menkes disease ... Optic neuropathy, Ataxia
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... Puncture, EEG Treatment ... prevention (statin for CVA ... diagnosis #management #treatment
Fusarium Treatment
 • Antifungal "susceptibility" can vary with Fusarium spp
 • F. oxysporum: low MICS to
Fusarium Treatment ... • Antifungal " ... and response to antifungals ... for disseminated disease ... enucleation Infectious Diseases
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Puberty Onset (BA = CA ... Puberty Onset (BA < CA ... • Cushing's Disease ... Panhypopituitarism Treatment ... Transplant Chronic Disease
Smoking Cessation and Nicotine Replacement Therapy (NRT)
Smoking is the leading cause of preventable death and a
multiple cancers, CV ... disease, stroke ... contraceptives, due to ↑ CV ... NRT #management #treatment
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... predominance) • CANOMAD (Ataxia ... Scleromyxedema (CNS+GI+CVS ... • Amyloidosis (CVS ... Sneddon-Wilkinson disease
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
goiter (Graves' disease ... Metastatic Follicular CA ... TRAb) if Graves' disease ... ↑ AST/ALT • Treatment ... tenderness Treatment