16 results
diagnosis hematology differential management mgus oncology gammopathy algorithm anemia causes cryoglobulinemia cryoglobulinemic lupus significance sle vasculitis ana anca antibodies antibody
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma and Monoclonal ... dL the ULN R - Renal ... /dL or CC < 40 ml ... if this is is monoclonal ... MGUS #diagnosis #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Monoclonal Gammopathy ... Cryoglobulinemia Renal-centered ... deposits: TMA w/ monoclonal ... ASanchez_PS #Monoclonal ... Differential #Diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... (HCV) • CLL & MBL ... Amyloidosis and monoclonal ... , retinal, DVT, ... Paraproteinemias #Hematology
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
arterioles) MONOCLONAL ... arthritis • Renal ... Vasculitis #Diagnosis #Rheumatology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... abnormal intact monoclonal ... : • Serum IgM monoclonal ... hyperCalcemia, Renal ... #Significance #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
disease (panuveitis, retinal ... involvement (uveitis or retinal ... Ocular: Giant retinal ... refractory disease : monoclonal ... signs #symptoms #rheumatology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
Renal involvement ... Mean eGFR - 39.5 mL ... /min • <60 mL/ ... TerrierBen #Renal ... Vasculitis #Management #Rheumatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... Renal Disease, Liver ... Myelodysplasia #Anemia #MCV ... Algorithm #Causes #Hematology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL ... probably < 1500ng/mL ... malabsorption) if < 200ng/mL ... Special cases (e.g. renal ... Measurement #SLE #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
scleroderma) - Anti-Scl ... polyangiitis without renal ... ANCA+ 30-60% • Renal-limited ... antibodies #diagnosis #rheumatology
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