831 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Wasting vs SIADH - Pathophysiology ... reabsorption 5) ↓ Na ... SaltWasting #SIADH #Pathophysiology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pharmacology and Pathophysiology ... 1) Na/K ATPase ... action of the Na ... increase, the Na ... #Pharmacology #Pathophysiology
Renin-Angiotensin-Aldosterone System (RAAS) 

The kidneys produce renin in response to low blood pressure or low plasma
or low plasma Na ... blood pressure and Na ... #Pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
65% of filtered Na ... 25% of filtered Na ... 8% of filtered Na ... tubule (CCT) - Na ... Segments #Function #Pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Stimulation of Na ... potassium #low #pathophysiology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Beta-Blockers Decreased Na ... #Hyperkalemia #Pathophysiology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
resistance • ↑ Na ... syndrome #Mechanisms #pathophysiology
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... inhibition • Increase Na ... nephrology #Effects #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Depolarization: • Na ... leading to a rapid Na ... Repolarization: • Na ... MOA: Block fast Na ... Classification #Classes #pathophysiology
EKG CHANGES AS A RESULT OF CHANGES IN NA OR K CHANNEL CONDUCTION - GRAPHIC BY
OF CHANGES IN NA ... JAMES LI, MD #Pathophysiology