157 results
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic ... C3 positive or negative ... mediated - DAT: IgG negative ... Pathophysiology #diagnosis ... #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... - Differential Diagnosis ... AIHA (7-8%) DAT-negative ... #Differential #Diagnosis ... #Table #hematology
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
DAT Results in Autoimmune ... Hemolysis DAT Negative ... antiglobulin #test #DAT #Autoimmune ... #Hemolysis #hematology ... #diagnosis
Causes of Leukocytosis and Leukopenia - Differential Diagnosis
 • Eosinophilia (AEC > 500, hypereosinophilia > 1500):
- Differential Diagnosis ... Infection, Malignancy, Autimmune ... Infections, Drugs, Autoimmune ... #Differential #Diagnosis ... #causes #hematology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Warm vs Cold Autoimmune ... Hemolytic Anemia Warm Autoimmune ... Splenectomy Cold Autoimmune ... Hemolytic #Anemia #hematology ... #diagnosis #comparison
Endocarditis Algorithm - Infective vs Noninfective Causes
Noninfective:
 • Malignancy
 • Autoimmune disease
 • Systemic infection
Native Valve
Malignancy • Autoimmune ... HACEK • Culture-negative ... epidermidis • Gram-negative ... Enterococcus • Gram-negative ... #Differential #Diagnosis
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential Diagnosis ... Hemolysis: • Autoimmune ... Anemias (AIHAs) • Alloimmune ... #Differential #Diagnosis ... #Algorithm #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
- Differential Diagnosis ... methotrexate) • Drugs Autoimmune ... CLL • APLA Alloimmune ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Anemia - Hemolysis Diagnostic Algorithm
Autoimmune hemolytic anemia
Microangiopathic hemolytic anemia
Probable thalassemia

Dr. Eric Strong @DrEricStrong - Strong Medicine
Anemia - Hemolysis Diagnostic ... Algorithm Autoimmune ... Anemia #Algorithm #hematology ... #diagnosis #differential
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Viral hepatitis, Autoimmune ... - Malignancy, Autoimmune ... Summary #table #comparison ... #diagnosis #hematology