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diagnosis treatment differential sle causes gout hematology table workup algorithm erythematosus nephrology summary systemic arthritis blood cerebritis classification cns coagulation
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... , oral ulcers, Lupus ... pANCA anti-MPO - Negative ... #Summary #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Drug-induced myopathy • Alcohol ... Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... differential #diagnosis #comparison ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
pANCA anti-MPO - Negative ... Usual therapeutic management ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Diagnosis of Lupus ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Algorithm Congenital Medications ... Bacteria • Gram Negative ... Destruction • Systemic Lupus ... Algorithm #Causes #Hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Anticoagulant Medications ... Liver Disease - Alcohol ... Summary #table #comparison ... #diagnosis #hematology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... BaillouChloe #Lupus ... #rheumatology # ... nephrology
Lupus Medication Titration - Treat-to-Target Algorithm Dr. Laurent ARNAUD @Lupusreference #Lupus #Medication #Titration #management #TreattoTarget #Algorithm #T2T #rheumatology
Lupus Medication ... Lupusreference #Lupus ... #Medication #Titration ... #management #TreattoTarget ... Algorithm #T2T #rheumatology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus ... #management
Approach to Gout Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals Treatment: • Weight loss, diet, d/c culprit
Needle-shaped, negative ... diet, d/c culprit medications ... gout #diagnosis #management ... treatment #ULT #rheumatology
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