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diagnosis infectiousdiseases infections atlas causes endocarditis galactomannan morphology pathology aspergillus betadglucan infective bcnie biomarkers culture hyphae infectious laboratory yeasts abscess
Fungal biomarkers Beta-d-glucan Aspergillus galactomannan By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com] #ID #Infectious Diseases #Infections #Differential #Ddx
Fungal biomarkers ... #Infections #Differential ... Ddx #Diagnosis #Fungal ... #Fungi #BDG #BDGlucan ... Aspergillus #Candida #Microbiology
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
cell response to fungi ... doesn't stain most fungi ... • India ink - "Negative ... staining #diagnosis #fungi ... #fungus #comparison
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
epidermidis - Gram-negative ... bacilli - Fungi ... ) - Culture negative ... bacilli - Fungi ... Pathogens #Diagnosis #Differential
Endocarditis Algorithm - Infective vs Noninfective Causes Noninfective: • Malignancy • Autoimmune disease • Systemic infection Native Valve
HACEK • Culture-negative ... epidermidis • Gram-negative ... bacilli • Fungi ... bacilli • Fungi ... Noninfective #Causes #Differential
Fungal Biomarkers: Comparing Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi •
Fungal Biomarkers ... component of many fungi ... febrilepodcast #Fungal ... Galactomannan #diagnosis #comparison ... #microbiology
Morphology of Fungal Infections in Tissues Fungal infections with hyphae or pseudohyphae in tissues: • Yeasts with
Morphology of Fungal ... Infections in Tissues Fungal ... Tissues #pathology #fungi ... yeast #hyphae #microbiology ... #differential #
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
Causes of Culture Negative ... Abscess - Differential ... as a cause of a negative ... Scedosporium, endemic fungi ... #Abscess #Differential
Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment:
Staphylococci (skin), Gram-negative ... difficile (gut) • Fungi ... Adenovirus, RSV • Fungi ... reactivation), RSV • Fungi ... Infections #Timeline #differential
Morphology and Descriptions of Fungal Infections with Hyphae or Pseudohyphae in Tissues Yeasts with Pseudohyphae: •
other hyaline fungi ... with dematiaceous fungi ... #fungi #infections ... #microbiology # ... differential #diagnosis
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
blood culture negative ... Tropheryma whipplei, Fungi ... BCNIE #Causes #differential ... causes #culture #negative ... InfectiousDiseases #Microbiology
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