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diagnosis differential treatment hematology algorithm neurology signs symptoms nephrology workup cardiology oncology anemia dermatology renal vasculitis endocrinology lupus summary classification
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Causes of false- ... negative SPEP: ... amyloidosis Other causes ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... involvement: Anti-GBM Disease ... Pauci-immune mediated (Negative ... diagnosis #algorithm #rheumatology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... by case) • Surgery ... #Syndrome #Treatment ... #management #pharmacology ... #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... Kasabach-Merritt syndrome ... Von Willebrand disease ... Gardner-Diamond syndrome ... #rheumatology #
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Causes of Pericardial ... Non-Infectious: • Rheumatologic ... : EGPA, Horton Disease ... , Takayasu Disease ... Differential #Diagnosis #Causes
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... ) • Rheumatic Diseases ... : IgG4-Related Disease ... (SPA) • Other Causes ... Differential #Diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... Evolution: Chronic disease ... #Summary #rheumatology
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
Causes of Culture ... antibiotics as a cause ... SAPHO, Sweet's Syndrome ... Autoimmune: Crohn's disease ... Auto-Inflammatory: SAPHO syndrome
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Tubular Proteinuria (Negative ... • Fanconi's syndrome ... Minimal change disease ... Diagnosis #Algorithm #Causes
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause ... CNS #neurology #rheumatology
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