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diagnosis treatment hematology differential lupus algorithm erythematosus syndrome systemic disease signs summary symptoms workup comparison criticalcare endocrinology arthritis blood checklist
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Anemia (AIHA) Pathophysiology ... C3 positive or negative ... mediated - DAT: IgG negative ... Hemolytic #Anemia #Pathophysiology ... #diagnosis #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... pANCA anti-MPO - Negative ... Usual therapeutic management ... Erythematosus #Diagnosis #Management ... #Summary #rheumatology
Coagulation Cascade and Anticoagulant Sites of Action - Amy Chung, MD, MSc https://twitter.com/AmyChung #AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Amy Chung, MD, MSc ... #Pharmacology #Pathophysiology ... Mechanisms #DOAC #Hematology
The principal endocrine 'axes' and glands. Parathyroid glands, adrenal zona glomerulosa and endocrine pancreas are not
Italics show negative ... abbreviations see ... Endocrinology #Pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... Erythematosus #SLE ... #MSK #Musculoskeletal ... Complications #pathophysiology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Anti-Ribo-P 5-15% If SLE ... higly specific for SLE ... patients with typical SLE ... Negative association ... erythematosus #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
pANCA anti-MPO - Negative ... Usual therapeutic management ... of SLE • Evolution ... comparison #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
dysmotility • MCTD (SLE ... • Specific for SLE ... Erythematosus #SLE ... Summary #diagnosis #rheumatology ... #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Disease, PRES Pathophysiology ... Erythematosus #SLE ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Pauci-immune mediated (Negative ... diagnosis #algorithm #rheumatology
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