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Classification, Differential Diagnosis, and Features of Hyponatremia According to Volume Status 

Hypervolemic hypernatremia 
 - CHF
, Differential Diagnosis ... - Nephrotic syndrome ... Glucocorticoid deficit - Hypokalemia ... #Differential #Diagnosis ... #Table #Causes
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... #Differential #Diagnosis ... #Algorithm #causes ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Diagnosis Algorithm ... • Refeeding syndrome ... vomiting) • Low ... #Algorithm #nephrology ... #low #potassium
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Algorithm Syndrome ... Malignancy True hypovolemia ... #Nephrology #Differential ... #Causes
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Algorithm Syndrome ... Malignancy True hypovolemia ... #Nephrology #Differential ... #Causes
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis ... EABV) - Consider: Hypovolemia ... Primary polydipsia, Low ... #algorithm #causes ... #nephrology
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... - Differential Diagnosis ... insipidus • Nephrogenic ... #Differential #Diagnosis ... #Causes #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... • Euvolemic (Low ... , Cushing syndrome ... #Differential #Diagnosis ... Workup #Algorithm #nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Diagnosis Algorithm ... #Hypokalemia # ... #Algorithm #nephrology ... #causes #low #potassium
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
- Cushing's syndrome ... Gestational DI, Nephrogenic ... Classification #Features #Diagnosis ... #Comparison #Table ... #Nephrology