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diagnosis management emergencies hemeonc mds myelodysplastic oncologic anemia aplastic cancer comparison differential diuresis diuretics excretion hemophagocytic hlh lymphohistiocytosis macrophage mas
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... • Early death Neutropenic ... : Tumor Lysis Syndrome ... coma SIADH: • Hyponatremia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... 10,000 ng/mL • Hyponatremia ... Treatment: • Corticosteroids ... MAS #Macrophage #Activation ... #Management #Hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
sequestration and activation ... without other cause ... : 33% • Treatment ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
• Hyponatremia ... Kidney stones caused ... Tolvaptan) • Treatment ... and euvolemic hyponatremia ... #Medications #Table
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... , breast CA - Hematologic ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Out Secondary Causes ... #diagnosis #hematology ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... Emergencies Neutropenic ... ): - Hematologic ... Treat underlying cause ... → no immediate treatment
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... caused by uncontrolled ... activation of the ... Syndrome) 3. ... Diagnosis #Management #Hematology
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