31 results
Rheumatoid Arthritis - 2020 ACR-EULAR Classification
≥ 6 of 10 points = definite RA
Joint Involvement:
2020 ACR-EULAR Classification ... joint) - 5 points Serology ... at least 1): Normal ... CRP and normal ... #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... values: WBC >100k ... values: Elevated ... diagnosis #management #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... Chronic Disease Normal ... #Anemia #MCV #Classification ... #Causes #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... Differential Diagnosis Algorithm ... Drug-induced AIHA - Abnormal ... Prosthetic heart valves ... #Causes #Hematology
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm

Elevated Hemoglobin:
 • Males: Hb > 16.5 g/dL/HCT ≥ 49%
 •
Differential Diagnosis Algorithm ... Hemoglobin: • Males ... Polycythemia - Acquired Causes ... ), TEMPI (VEGF normal ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... RBC Production - Normal ... Non-lmmune #Anemia #Classification ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Idiopathic • Normal ... differential #diagnosis #algorithm ... #rheumatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... splenomegaly, abnormal ... neurology, back ... pain Haematology ... #Limping #NWB #Algorithm
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... • Normal kidney ... Classification: ... Hepatorenal #Syndrome #Hepatology ... #Nephrology #Diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... can have extra nodal ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #Hematology #Diagnosis