69 results
diagnosis management algorithm differential oncology syndrome dermatology lupus vasculitis acr2021 causes classification disease guidelines sle workup arteritis clinical coagulation doac
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
or priapism • Lab ... values: WBC >100k ... , + lab signs of ... values: Elevated ... diagnosis #management #hematology
Thromboelastogram Interpretation Reaction Time (R Value): - Time till initiation of fibrin clot - Treatment: FFP, protamine K
Reaction Time (R Value ... fibrin clot - Treatment ... , protamine K value ... interaction - Treatment ... #coagulation #hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Laboratory • Normal ... type 2B) • Normal ... PT/INR • Normal ... factor VIII) Treatment ... Disease #Diagnosis #Hematology
Rheumatoid Arthritis - 2020 ACR-EULAR Classification ≥ 6 of 10 points = definite RA Joint Involvement:
negative anti CCP Ab ... positive anti CCP Ab ... at least 1): Normal ... CRP and normal ... Classification #rheumatology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Algorithm Relative - Normal ... Positive - Low/Normal ... Saturation 90%, Abnormal ... Abdominal Ultrasound ... Algorithm #Causes #Hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
±AKI Initial labs ... hemosiderin • PT/aPTT normal ... Management #Algorithm #hematology
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
ristocetin • Normal ... platelet morphology — normal ... cytometry— GP lb ... defects of GP lb ... Platelet #disorders #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
• Muscular: normal ... CK, normal biopsy ... diagnosis #management #treatment ... #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
marrow) -dys- (abnormal ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Cytopenias • Cardiac valve ... , Serositis Labs ... flares • CRP normal ... Erythematosus #Diagnosis #Rheumatology
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