75 results
Bayesian combination of 4T score with Heparin PF4 antibody titer to obtain the post-test probability of
4T score with Heparin ... PulmCrit #4TScore #Heparin ... PF4Antibody #Bayesian #Diagnosis ... #Hematology #HITT ... Thrombocytopenia #Laboratory
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... GI. uterine) Laboratory ... PT/INR • Normal ... VonWillebrand #Disease ... #Diagnosis #Hematology
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Investigation of Abnormal ... #Coagulation #Abnormal ... #APTT #Laboratory ... #Hematology #Diagnosis
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
an inhibitor of normal ... to have 50% of normal ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
- Differential Diagnosis ... Hepatic, Portal, ... • Gaucher's Disease ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Malabsorption (e.g. celiac disease ... Medications - Heparin ... Advanced Liver Disease ... Summary #table #comparison ... #diagnosis #hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
inhibitor • Liver disease ... elevated in: • Heparin ... Thromboplastin #laboratory ... #hematology #diagnosis
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Causes of Ascites Normal ... Veno-occlusive disease ... Liver disease ... Ascites #Causes #diagnosis ... #differential #hepatology
Causes of Portal Hypertension According to Site of Vascular Obstruction
1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
Schistosomiasis, Congenital hepatic ... Veno-occlusive disease ... 5) Post-hepatic ... #differential #diagnosis ... #causes #hepatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... • Muscular: normal ... CK, normal biopsy ... splenomegaly • Hepatic ... #treatment #rheumatology