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differential management algorithm causes table anemia hepatology oncology rheumatology classification liver pathophysiology syndrome appearance coagulation lesions radiology thrombocytopenia abnormal alopecia
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Medications - Heparin ... • Acute DIC - Septic ... Summary #table #comparison ... #diagnosis #hematology ... #deficiency
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency • B12 Deficiency: MMA elevated,
B12 and Folate Deficiency ... • B12 Deficiency ... : MMA normal, Homocysteine ... #VitaminB12 #diagnosis ... #hematology
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
clotting factor deficiency ... Patient has a factor deficiency ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
of Anemia with Normal ... - Differential Diagnosis ... • Early Iron Deficiency ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... effect following treatment ... malignancy • Iron deficiency ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
• Vitamin K deficiency ... • Factor VII deficiency ... elevated in: • Heparin ... Thromboplastin #laboratory #hematology ... #diagnosis
Diagnosing Vitamin B12 and/or Folate Deficiency It turns out that simply measuring serum levels of B12 or
Diagnosing Vitamin ... inadequate to diagnosis ... people with low normal ... B12 stores have normal ... #Hematology #ComparisonTable
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... • Dietary Deficiency ... B12 and Folate Deficiency ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
mevalonate kinase deficiency ... CK, normal biopsy ... splenomegaly • Hepatic ... #management #treatment ... #rheumatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... 80 fL) • Iron Deficiency ... Chronic Disease Normal ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
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