62 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... - Differential Diagnosis ... Reticulocytes • Abnormal ... #Differential #Diagnosis ... #Algorithm #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... syndrome (ST-HUS ... anemia" • HELLP syndrome ... #differential #diagnosis ... #hematology #hemolysis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
- Differential Diagnosis ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... - Differential Diagnosis ... Table Warm AIHA ... #Autoimmune #Hemolytic ... #Table #hematology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Cold Autoimmune Hemolytic ... Warm Autoimmune Hemolytic ... Cold Autoimmune Hemolytic ... #Anemia #hematology ... #diagnosis #comparison
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... uremic syndrome ... #differential #diagnosis ... #hematology #anemia
Isolated Hyperbilirubinemia - Differential Diagnosis Algorithm
Direct Hyperbilirubinemia: Dubin-Johnson Syndrome, Rotor Syndrome
Indirect Hyperbilirubinemia: 
 - Trauma, Hematoma,
- Differential Diagnosis ... Reticulocyte Count Normal ... : Hemolysis, Dyserythropoiesis ... #Differential #Diagnosis ... #Algorithm #hepatology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
thrombocytopenic purpura/hemolytic ... uremic syndrome ... thrombocytopenia, Hematology ... 2012, p 193 #Diagnosis
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Intravascular Hemolysis ... - Differential Diagnosis ... Drug-induced AIHA - Abnormal ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... blood loss, Acute hemolysis ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology