31 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... - CRP: Usually normal ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... of SLE versus DIL ... • Immunologic Workup ... life-threatening • Treatment ... Management #Summary #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... Glucocorticoids, IL ... #Algorithm #hematology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SLE : systemic lupus ... LungDisease #CTILD #Diagnosis ... #Differential #Comparison ... #Table #Pulmonary ... #Rheumatology #
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... and first-line treatment ... thrombocytopenia #Comparison ... #Diagnosis #Table ... #Hematology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Elevated ESR, Normal ... muscle weakness • Normal ... uncommon 5-15% of lupus ... #differential #diagnosis ... #comparison #rheumatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
CRP - Usually normal ... • Immunologic Workup ... constitutional symptoms • Treatment ... #DIL #rheumatology ... #diagnosis #treatment
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... MAS, Visceral, DIC ... CK, normal biopsy ... #management #treatment ... #rheumatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Post-partum • Acute DIC ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
schistocytes, DIC ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table