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Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Autoimmune • ITP ... HELLP Syndrome • TTP ... Diagnosis #Algorithm #Causes
Nucleated red blood cells, aka normoblasts or erythroblasts, were released prematurely from the bone marrow in
Nucleated red blood ... The other nucleated ... fetus/newborn the causes ... #Blood #Smear #Nucleated
Cardiac Tamponade - Guidelines for Crises in Anaesthesia Caused by an accumulation of blood, pus, effusion fluid
in Anaesthesia Caused ... or iatrogenic causes ... needle + 3-way tap ... of underlying cause ... • Identify tip
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... MALIGNANCY: - TMA: TTP ... HIT - MAHA: TTP
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... decrease in most cases ... schistocytes, nucleated ... hematuria (without casts ... impairment #TTP
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... Thrombocytopenia: ITP ... • Secondary Causes ... disease - DIC/TTP ... Defects: • DIC, TTP
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... Microangiopathy: DIC, TTP ... Antibody-mediated: ITP
Thrombotic Microangiopathy - TMAs 1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
almost) all TMAs cause ... TMA is due to TTP ... compliment-mediated TTP ... TTP is only TMA ... suggests against TTP
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP ... implications : TTP ... confirmatory testing for TTP ... thrombocytopenic #purpura #TTP
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... fulminans - DIC - TTP ... Non-Palpable Rash: - ITP ... APLS - HIT - ITP ... Diagnosis #Algorithm #Causes
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