9 results
diagnosis differential causes hematology algorithm basophilia basophils classification enlarged high hyperkalemia leukemia neuropathy oncology peripheral platelets potassium secondary spleen splenomegaly
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
hemorrhage) • Chronic ... inflammatory disorders ... Myelofibrosis (MF) • Chronic ... myeloid leukemia ... Diagnosis #Causes #hematology
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
A (AA) → Chronic ... Inflammatory Conditions ... Bronchiectasis, Chronic ... the extent of disease ... AA Protein: Chronic
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Polycythemia Vera • Chronic ... : • Acute or Chronic ... Inflammatory: ... disorders • Celiac disease ... Algorithm #Causes #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Non-Malignant • Amyloidosis ... • Gaucher's Disease ... vera, essential thrombocytosis ... myelofibrosis) Inflammatory ... Algorithm #Causes #Hematology
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
Syphilis, Lyme disease ... , Leprosy • Inflammatory ... , Sarcoidosis, Amyloidosis ... myeloma, secondary amyloid ... diagnosis #causes #neurology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... → Refer to hematology ... myelosuppressive agents • Inflammatory ... Vasculitides, IBD, Celiac disease ... • Infections: Chronic
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Disorders: • Chronic ... myeloid leukemia ... Hypersensitivity Or Inflammatory ... Colitis and Crohn’s Disease ... Diagnosis #causes #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... Myeloid Leukemia ... basophilia, and thrombocytosis ... #Leukemia #Hematology
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Cellular efflux; thrombocytosis ... nonsteroidal anti-inflammatory ... Chronic kidney disease ... : SLE, amyloidosis ... Chronic kidney disease
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