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management differential rheumatology hematology microbiology clinical syndrome chronic dermatology msk neurology oncology arthritis chagas classification hemophagocytic hiv hlh lymphohistiocytosis microscopy
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Causes of Fever ... - Differential Diagnosis ... • Infection: ... , Sarcoidosis, Adult ... #Differential #Diagnosis
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm Neoplasm: • NHL • Hodgkin's lymphoma • Leukemia • Solid
Causes of Fever ... - Differential Diagnosis ... • Trauma Non-infectious ... • Lyme disease ... #Algorithm #causes
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... triad: Fever, Arthralgia ... : • Infectious ... Complications: MAS ... #treatment #rheumatology
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... and bacterial infections ... leishmaniasis • Adult ... Causes: • Still's ... #Differential #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... : SLE+++, Adult-onset ... Still disease, ... Drugs, Unknown cause ... Treatment: •
Causes of Hypercalcemia due to increased Vitamin D levels • The BIG 3:
Causes of Hypercalcemia ... Tuberculosis • Fungal Infections ... CYP24A1 mutation (adult ... pneumonia, Cat scratch fever ... #differential #diagnosis
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
rarely occurs in adults ... Presentation: • Fever ... , Cough • +/-Nausea ... - Fever lasting ... #management #treatment
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... susceptibility, infectious ... : High spiking fever ... Systemic AOSD: high fever
Tularemia - Diagnosis and Management Summary Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection •
Coccobacillus - Zoonotic Infection ... Ulceroglandular: Fever ... More common in adults ... : • Severe Disease ... #infectiousdiseases
Hantavirus Pathogen: Hantavirus - Rodents are the primary reservoir Transmission: • Shed in the urine, feces, saliva of
common route of infection ... • Prodrome: fever ... +/- diarrhea Diagnosis ... #management #treatment ... #microbiology #infectiousdiseases
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