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diagnosis differential causes anemia management elevatedmcv indications macrocytosis microcytic rbc atlas bloodbank bloodcell cerebritis chronic cns conditions disorders electrophoresis enlarged
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic Algorithm ... in peripheral blood ... High in acute blood ... of substrate (e.g ... Diagnosis #Workup #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Normal Blood Smear ... • Drugs Oval Macrocytes ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Infections Macrocytic ... aciduria, Drugs (e.g ... #Anemia #MCV #Algorithm ... Differential #Diagnosis #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Differential Diagnosis Algorithm ... • Thrombus (e.g ... Non-Malignant • Amyloidosis ... Myeloproliferative disorders (eg ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g ... #Causes #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Iron Deficiency (Eg ... Causes: Chronic Blood ... Other • e.g ... #Microcytic #Anemia ... #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Differential Diagnosis Algorithm ... • Secondary (e.g ... Polychromatic Macrocytes ... Polychromatic Macrocytes ... #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... anemia (sometimes) Macrocytic ... Chemotherapy (e.g ... disease, McLeod blood ... differential #diagnosis #hematology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Rheumatic fever • Amyloidosis ... disease, Vasculitis (e.g ... Macroglossia - Amyloidosis ... arteritis • Bloody ... differential #diagnosis #rheumatology
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
macroglobulinemia, primary amyloidosis ... suspected • Hypercalcemia ... possible malignancy (e.g ... on peripheral blood ... Electrophoresis #SPEP #Hematology
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