36 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
hemorrhagic skin lesions ... vascular disorders, coagulation ... deficiency • Liver ... Differential #Diagnosis #hematology ... #rheumatology #
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
ASA) • Renal Disease ... Von Willebrand's Disease ... Iatrogenic) • Liver ... Disease • Vitamin ... Algorithm #Causes #Hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Summary of Coagulation ... ) • Advanced Liver ... Disease - Alcohol ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
presents with coagulation ... pregnancy * Severe coagulation ... defects and liver ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty Liver ... presents with coagulation ... pregnancy * Severe coagulation ... AFLP #obstetrics #hematology ... #diagnosis #table
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... for refractory lesions ... or refractory lesions ... #pharmacology #rheumatology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
hemorrhage, while under-coagulation ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... DIC • Severe Liver ... Disease: - Impaired ... + Bleeding Treatment ... #management #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... months without treatment ... disease, liver ... Kidney Failure Coagulation ... Failure #Cirrhosis #Hepatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and their Disease ... Dermatomyositis Anti-LKM (liver ... (TTG) - Celiac disease ... #diagnosis #table ... #rheumatology #