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diagnosis differential algorithm clinical hepatology jaundice photo ucsdh bilirubin bilirubinemia conjugated gastroenterology icterus ophthalmology pediatrics physicalexam scleral video classification color
Opisthotonos on Physical Examination Opisthotonos in a 5 day baby referred from a peripheral facility with jaundice
Opisthotonos on ... Examination Opisthotonos ... DDx: Kernicterus ... TheIntern254 #Opisthotonos ... #Kernicterus #clinical
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 Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Non-hemolytic Disorders of Hyperbilirubinemia ... common hereditary hyperbilirubinemia ... • Unconjugated hyperbilirubinemia ... rarely results in kernicterus ... and stress may cause
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
to Conjugated Hyperbilirubinemia ... non-ICU vs ICU causes ... #Conjugated #Hyperbilirubinemia
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Unconjugated hyperbilirubinemia ... posthepatitis hyperbilirubinemia ... reactions) Conjugated hyperbilirubinemia ... miscellaneous causes ... #differential #causes
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
- Unconjugated Hyperbilirubinemia ... Hepatic - Conjugated Hyperbilirubinemia ... Diagnosis #Algorithm #Causes
Approach to Neonatal Jaundice Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Neonatal Jaundice Causes ... of pathologic hyperbilirubinemia
Hyperphosphatemia - Differential Diagnosis Algorithm Transcellular Shift: • Rhabdomyolysis • Tumor Lysis • Metabolic or Respiratory Acidosis
Multiple Myeloma Hyperbilirubinemia ... endocrinology #causes
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Interference • Hyperbilirubinemia
Causes of Growth Discrepancy: Large for Gestational Age - Differential Diagnosis Algorithm Maternal Factors: • Multiparity •
Causes of Growth ... Perinatal asphyxia • Hyperbilirubinemia ... Diagnosis #Algorithm #Causes
Urine Color - Differential Diagnosis Red Urine: • Medical conditions: bleeding, porphyria, factitious disorder • Meds: rifampin,
Medical conditions: hyperbilirubinemia ... Urine: • Any cause ... dyes typically cause
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