11 results
diagnosis differential hemolysis algorithm causes extravascular intravascular management treatment anemias antibody antiglobulin cold dat direct disease pathophysiology table test testing
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... hemoglobinuria) • Cold Agglutinin ... #Hemolytic #Anemia ... Diagnosis #Table #hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... : • Autoimmune ... Hemolytic Anemias ... (AIHAs) • Alloimmune ... Diagnosis #Algorithm #hematology
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic ... Anemia (AIHA) Pathophysiology ... #Autoimmune #Hemolytic ... #Anemia #Pathophysiology ... #diagnosis #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... Hemolytic Anemia ... 1) DIAGNOSE AIHA ... #Hemolytic #Anemia ... management #treatment #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... (AIHA) "Warm" ( ... . primary cold agglutin ... differential #diagnosis #hematology ... #anemia
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... #Autoimmune #Hemolytic ... #Anemia #AIHA # ... Treatment #management #hematology
Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG (
DAT Results in Autoimmune ... ), C3d ( - ) WAIHA ... ( +/- ) Cold agglutinin ... antiglobulin #test #DAT #Autoimmune ... #Hemolysis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
women • 15% of AIHA ... Viral infection, autoimmune ... anemia • Cold ... CLL (older) • Autoimmune ... #anemia #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
• Cold AIHA ... • Alloimmune ... • Drug-induced AIHA ... anemia • ... Algorithm #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Agglutination - Cold agglutinins ... elliptocytosis, autoimmune ... #Anemia #Differential ... Algorithm #workup #hematology
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