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diagnosis differential anemia causes management mcv product reactions agglutinin anemias calculation classification cold deficiency disease disorders eosinophil eosinophilia ferritin focal
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Differential Diagnosis Algorithm ... Signs of anemia ... Hypersplenism, Infection ... Matthew Ho, MD PhD ... #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Macroangiopathic, Infections ... aciduria, Drugs (e.g ... Matthew Ho, MD PhD ... Differential #Diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... , Acute hemolysis ... Matthew Ho, MD PhD ... #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
the peripheral blood ... > 3: • Acute blood ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... • Compensated hemolysis ... Immunoglobulin M (IgM) • Blood ... sensitize red blood ... #anemia #hematology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Differential Diagnosis Algorithm ... (e.g. ... Lymphadenopathy #LAD ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... • Peripheral blood ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Differential Diagnosis Algorithm ... • Bleeding • Hemolysis ... Chronic Disease (e.g ... Inflammation, Chronic Infection ... #Causes #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Differential Diagnosis Algorithm ... TSAT, sTfR • Blood ... extravascular) hemolysis ... Matthew Ho, MD PhD ... #ferritin #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
in peripheral blood ... High in acute blood ... loss, hemolysis ... of substrate (e.g ... Diagnosis #Workup #Hematology
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