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diagnosis differential causes hemolytic oncology workup thrombocytopenia blood lymphadenopathy macrocytic mcv platelets thrombocytosis agglutinin allergy anemias bandemia cbc chronic classification
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Differential Diagnosis Algorithm ... Signs of anemia ... Hypersplenism, Infection ... Matthew Ho, MD PhD ... #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... deficiency • Lead ... aciduria, Drugs (e.g ... Matthew Ho, MD PhD ... Differential #Diagnosis #hematology
Thrombocytopenia - Differential Diagnosis Algorithm Decreased production: • Bone marrow suppression • Bone marrow failure • Bone
Differential Diagnosis Algorithm ... infiltration • Infection ... Connective tissue disorders ... Matthew Ho, MD PhD ... #hematology #platelets
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Differential Diagnosis Algorithm ... Infection • ... Solid Tumour (e.g ... • Metabolic disorders ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Differential Diagnosis Algorithm ... Thalassemia • Lead ... Chronic Disease (e.g ... Inflammation, Chronic Infection ... #Causes #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Differential Diagnosis Algorithm ... Lymphoid (ALL) - PAS ... Pelger-Huet, Macrocytic anemia ... #hematology #Markers ... Differential #Diagnosis #Algorithm
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Differential Diagnosis Algorithm ... (e.g. ... Lymphadenopathy #LAD ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... Vasculitis • Infection ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... → Refer to hematology ... hemolysis, deficiency anemia ... Matthew Ho, MD PhD ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... lymphoproliferative disorders ... disease, Copper and lead ... differential #diagnosis #hematology ... #anemia
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