66 results
diagnosis management differential algorithm oncology neurology anemia hemolytic hemophagocytic hlh lymphohistiocytosis vasculitis classification clinical dermatology disease syndromes thrombocytopenia arthritis erythematosus
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... methotrexate) • Drugs Autoimmune ... Non-lmmune: • HELLP Syndrome ... Vasculitis • Infection ... #Hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Diagnosis Algorithm Signs ... Hemolysis: • Autoimmune ... Hypersplenism, Infection ... Matthew Ho, MD PhD ... Diagnosis #Algorithm #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... Extravascular #Causes ... differential #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... inflammatory disorders (e.g ... . autoimmune, TB ... Myelodysplastic syndrome ... #hematology #secondary
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... , holster sign, ... anti-synthetase syndrome ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... Constitutional disorders, eg ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... thrombocythemia), Autoimmune ... vonWillebrand #Syndrome ... Diagnosis #Management #treatment ... #hematology #differential
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Severe Disease → Remission
Polyarteritis Nodosa (PAN ... immunosuppressive agent (e.g ... @MithuRheum #PAN ... Vasculitis #Management #Treatment ... Guidelines #algorithm #rheumatology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... (e.g. ... Lymphadenopathy #LAD ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
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