37 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Vesicopustule on erythematous ... Schönlein purpura • PAN ... Antiphospholipid-antibody syndrome ... Discoid lupus erythematosus ... differential #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... Demyelinating Syndrome ... Lumbar Puncture, EEG ... Treatment: ... #rheumatology #
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... polymyositis overlap syndrome ... severe disease Treatment ... diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... . hematologic) ... vein thrombosis Hematologic ... #Diagnosis #Rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Toxic Damage (e.g ... Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... Vasculitis • Infection ... Algorithm #Causes #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
[SLE], AOSD) • ... Infection (eg, ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines
 • Severe Disease → Remission
Polyarteritis Nodosa (PAN ... immunosuppressive agent (e.g ... @MithuRheum #PAN ... Vasculitis #Management #Treatment ... Guidelines #algorithm #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... Demyelinating syndromes ... #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Bacterial or viral infection ... disease, Vasculitis (e.g ... ., PAN) • Seizures ... Cardiomyopathies - Viral infection ... differential #diagnosis #rheumatology