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hematology causes workup management disorders classification hemolytic pancytopenia syndrome atlas elevatedmcv elevation generalized hemolysis hepatology injury leukemia liver macrocytic macrocytosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm ... Blood Loss ... • Acute Bleed - ... Deficiency • Aplastic ... #Diagnosis #Algorithm
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential ... Diagnosis Algorithm ... Signs of anemia ... Diagnosis #Algorithm ... #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Diagnosis Algorithm ... • Marrow Aplasia ... Normal RBCs • Acute ... Diagnosis #Algorithm ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... Diagnosis Framework ... Non-hemolytic: ACD, Aplastic ... Diagnosis #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... Diagnosis: • Pancytopenia ... progress to MDS or acute ... #Anemia #diagnosis
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
marrow failure: Aplastic ... Index > 3: • Acute ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... result from low blood ... #Anemia #oncology ... #hematology #diagnosis
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Diagnosis Algorithm ... • Toxins • Aplastic ... Anemia • Myelodysplasia ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Diagnosis Algorithm ... Fatigue • Acute ... #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... #Diagnosis #Algorithm ... #Causes #Hematology
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