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diagnosis differential management causes aplastic chronic cll lymphocytic thrombocytosis classification dermatology diffuse erythematosus gap globulin hemeonc hodgkins lad leukemoid leukocytosis
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
malignancy: • Symptoms ... : B-symptoms, bruising ... hepatomegaly • Labs: anemia ... #hematology #WBC ... #Leukemoid
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Differential Diagnosis Algorithm ... Fatigue • Acute ... Differential #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Differential Diagnosis Algorithm ... Artifact (redo CBC ... Chronic Myelogenous Leukemia ... Infectious: • Acute ... Iron deficiency anemia
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Differential Diagnosis Algorithm ... Normal RBCs • Acute ... Inflammation • Cancer ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... with no early symptoms ... Physical Exam/Signs ... #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... lymphoid organs When Cancer ... #Hematology #Oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... progress to MDS or acute ... leukemia • Associated ... management #treatment #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... for workup, including ... , deficiency anemia ... Malignancy: Metastatic cancer ... Differential #Diagnosis #Algorithm
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Most common leukemia ... Vmphocytosis on routine CBC ... of anemia or thrombocytopenia ... marrow failure with anemia ... #oncology #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... (MCV): Average RBC ... High in acute blood ... #Workup #Hematology
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