32 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Reactive: - Systemic ... Fatigue • Acute ... Age > 50 • Chronic ... Algorithm #Causes #Hematology ... #Oncology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Chronicity: • Acute ... rheumatic fever • Chronic ... hepatitis, herpes • Chronic ... #rheumatology # ... approach #workup
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
pericarditis • Hepatic: PBC ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Artifact (redo CBC ... Infectious: • Acute ... or Chronic Inflammatory ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... , deficiency anemia ... • Infections: Chronic ... Diagnosis #Algorithm #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Blood Loss • Acute ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Algorithm #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... Spherocytes, RBC ... Algorithm #Causes #Hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
phenomenon (20%) Joints ... Arthritis in small joints ... ) Blood (75%): Anemia ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
transform into a RBC ... of chronic inflammation ... deficiencies: Chronic ... Index > 3: • Acute ... Production #Index #hematology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
Summary Overview: chronic ... involving small joints ... knees, shoulders Signs ... ideally limit for acute ... diagnosis #management #rheumatology