43 results
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Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
== Decreased RBC ... Hypertriglyceridemia • Uremia ... turnover • Acute ... • Hemolytic anemia ... End-stage renal disease
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... , Liver diseases ... Malignant tumors, Acute ... , Liver diseases ... coagulopathy (DIC) #RBC
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Blood Loss • Acute ... • Anemia of Chronic ... Disease • Marrow ... Non-lmmune #Anemia
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... Signs and Symptoms ... but elevated as disease ... pregnancy, Cardiac diseases ... , IgG4 related disease
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Summary Clinical Signs ... demineralization) • Renal disease ... hypercalcemia) • Anemia ... plus one of: • Anemia ... Diagnosis #Management #oncology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... Index < 2: • Anemia ... Chronic kidney disease ... Index > 3: • Acute ... , Intrinsic RBC
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... biliary cirrhosis (PBC ... with systemic diseases ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Infectious: • Acute ... disorders • Celiac disease ... Iron deficiency anemia
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Presentation: Subacute-Acute ... • Rare: DAH, acute ... , Anaphylaxis, Acute ... management #hematology #oncology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... • Autoimmune diseases ... 21% had normal WBC ... #CBC #hematology ... #pathophysiology
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