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diagnosis hematology causes classification management thrombocytosis approach blood calculation cll diffuse disorders elevated gravis hodgkins index injury lad leukemia lymphadenopathy
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... Blood Loss • Acute ... Deficiency • Aplastic ... of Chronic Disease
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Diagnosis Algorithm ... • Marrow Aplasia ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Artifact (redo CBC ... Infectious: • Acute ... effect following treatment ... Iron deficiency anemia
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... deficiencies: Chronic ... marrow failure: Aplastic ... Index > 3: • Acute ... #differential #
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Diagnosis Algorithm ... Fatigue • Acute ... Age > 50 • Chronic ... #Diagnosis #Algorithm ... Causes #Hematology #Oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... hematology for workup ... hemolysis, deficiency anemia ... Rebound effect from treatment ... • Infections: Chronic
Non-ACS Myocardial Injury - Elevated Troponin Differential Diagnosis and Workup Algorithm • Chronic Myocardial Injury: End
Diagnosis and Workup ... Algorithm • ... Chronic Myocardial ... (ie Sarcoid), Chronic ... Shock, Hypoxemia, Anemia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... Pure red cell aplasia ... ’s lymphoma or acute ... #oncology #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm ... Acute • Myloid ... T-cell - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Aplastic Anemia ... Marrow Failure • Chronic ... blood count with differential ... diagnosis #hematology #oncology
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