38 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Diagnosis Algorithm Signs ... of anemia and hemolysis ... • Extrinsic RBC ... • Intrinsic RBC
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... • Symptomatic anemia ... Treatment: • Consider ... diagnosis #management #treatment
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... ↑ LDH • Anti-RBC ... Autoimmune #Hemolytic #Anemia ... diagnosis #management #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
fever - ACS, AKI ... >100k, + lab signs ... organ damage • Treatment ... Low calcium • Treatment ... - Hyperkalemia treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... Treatment:
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Artifact (redo CBC ... effect following treatment ... Iron deficiency anemia
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
: • Vit B12 - aka ... wt loss • If anemia ... • Labs: - CBC ... , PBS - anemia, ... Check for IF ab Treatment
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
suspected: • Signs ... Iron-deficiency anemia ... unresponsive to treatment ... discernable cause • Signs
Balanced Crystalloids vs. NormalSaline - My infographic about SALT-ED and SMART trial comparing crystalloids and saline
hospital-free days between treatment ... with BC and NS ... - Stage 2 AKI ... Crystalloids #Saline #AKI
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Vmphocytosis on routine CBC ... 5) Symptoms of anemia ... transformation) Treatment ... marrow failure with anemia ... AIHA, PRCA) • Treatment