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diagnosis differential hematology oncology algorithm renal workup aplastic barre cardiology classification disease encephalopathy guillain interpretation leukemia pharmacology sclerosis symptoms table
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
DIAGNOSE AIHA • Anemia ... ↑ LDH • Anti-RBC ... 2) LOOK FOR a cause ... #diagnosis #management ... #treatment #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute ... #treatment #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... Treatment: • Consider ... progress to MDS or acute ... #diagnosis #management ... #treatment #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Infectious: • Acute ... effect following treatment ... Iron deficiency anemia ... #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
count cause hyperviscosity ... - ACS, AKI, acute ... >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... pain hematuria syndrome ... hematuria • Signs ... • Nutcracker syndrome ... #urology #nephrology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... diagnosis and treatment ... Inflammatory causes ... • Acute disseminated ... #neurology #inflammatory
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... • ↓ WBC • ↓ ... Treatment: ... #oncology #hematology ... #diagnosis #management
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... osmolarity If cause ... clinical context and signs ... Differential #Diagnosis #nephrology ... #causes
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
suggestive of acute ... in a variety of acute ... suggestive of nephrotic sydnrome ... : • RBC Casts - ... Urine #Microscopy #nephrology
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