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diagnosis differential management hematology workup algorithm symptoms oncology pulmonary clinical dermatology rheumatology syndrome anesthesia anesthesiology cardiology hepatology neurology infectiousdiseases intraoperative
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... • Anemia of Chronic ... Disease • Marrow ... #Classification ... Diagnosis #Algorithm #Causes
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Poisoning • Anemia ... Marrow Failure • Anemia ... #MCV #Classification ... Diagnosis #Algorithm #Causes
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... == Decreased RBC ... Hypertriglyceridemia • Uremia ... • Hemolytic anemia ... End-stage renal disease
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
suspected: • Signs ... Iron-deficiency anemia ... unresponsive to treatment ... without discernable cause ... • Signs of osteoporosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Artifact (redo CBC ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
for Hemolytic Anemia ... Intrinsic Causes ... : • Liver disease ... #Hemolytic #Anemia ... #classification
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... ↑ LDH • Anti-RBC ... 2) LOOK FOR a cause ... diagnosis #management #treatment
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... Signs and Symptoms ... but elevated as disease ... pregnancy, Cardiac diseases ... , IgG4 related disease
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
decreased PLT count: CBC ... PT, aPTT(liver disease ... changes), high MCV anemia ... bypass), LFT (liver disease ... ), HBsAg/anti-HBc
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Neutrophils - Low RBC ... • Pancreatic Disease ... • Liver Disease ... Diagnosis #Algorithm #Causes
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