72 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... symptomatology Differential ... Diagnosis for Pulmonary ... #differential # ... diagnosis #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
- Na-K-2Cl cotransporter ... limb Gitelman syndrome ... Thiazide-sensitive NaCl ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Smith, Sm/RNP, Scl ... body-like: - Neurologic ... ARUPConsult @ARUPLabs #ANA ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... initiation • Differential ... #management #hematology
Pulmonary Complications Following Stem Cell Transplant

For patients in the pre- engraftment period (day 0-30):
 - 
Pulmonary
- Engraftment syndrome ... ,mycobacteria, and ... fungal- PCP, aspergillus ... tissue disorders #Diagnosis ... #Differential #
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... - Diagnosis and ... Management • ... #Diagnosis #Management ... #differential
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... #management #treatment
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... With associated pulmonary ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Diagnosis Algorithm ... Weakness • Cardio-pulmonary ... Motor Neuron and ... Lambert-Eaton Myasthenic Syndrome ... Peripheral #Weakness #Neurology
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... cirrhosis, nephrotic syndrome ... Stress, Nausea, Pulmonary ... #Hyponatremia #Differential ... #diagnosis #nephrology