52 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... : Acute blood loss ... Rebound effect from treatment ... #Algorithm #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... the total white blood ... during an allergic reaction ... Or Inflammatory Reactions ... #causes #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... of high parity blood ... without other cause ... #hematology #diagnosis ... #comparison #table
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... allergy, drug reaction ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... AIHA, Transfusion reactions ... Drug-associated, PCH ... - Peripheral Blood ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... old, ~10,000 new cases ... only curative treatment ... #Management #treatment ... #hematology #oncology
Kerion
Raised, boggy lesion with heaped up purulent nodules 
Caused by host's response to a fungal ringworm
purulent nodules Caused ... Lymphadenopathy Treatment ... Griseofulvin #Kerion #Dermatology ... #Diagnosis #Management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Criteria for Diagnosis ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology ... #diagnosis #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... more likely to cause ... #Transfusion #diagnosis ... #management #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Hemolytic Anemia 1) DIAGNOSE ... type ± C3d • Blood ... 2) LOOK FOR a cause ... #management #treatment ... #rheumatology