22 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
defects. 1) HELLP (Hemolysis ... Elevated Liver tests ... #obstetrics #hematology ... #diagnosis #table ... #comparison
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Cold Autoimmune Hemolytic ... Spherocytes • Treatment ... • Treatment: Warm ... #Anemia #hematology ... #diagnosis #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... Elevated Liver tests ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Drug-associated, PCH ... , Evans Syndrome ... Laboratory Tests ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
necrosis HELLP Syndrome ... (Hemolysis, Elevated ... of Pregnancy (AFLP ... obstetrics #hepatitis #comparison ... #differential #diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Diagnosis: • hemolytic ... Test: Donath-Landsteiner ... test #cold # ... #anemia #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... extrahepatic source - Tests ... • Gilbert's syndrome ... #differential #diagnosis
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
presence of metabolic syndrome ... Areas of diagnostic ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology ... #Differential #Diagnosis
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Diagnostic Criteria ... for Sweet Syndrome ... Excellent response to treatment ... count >10 x 10^3/pL ... #Hematology #Dermatology